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First of all, claiming money back from one's losses cannot be done from an overall net loss.  On the other hand, reducing one's taxes through gambling losses can only be done if these losses offset one's casino winnings.  In other words, you are required to report your winnings in addition to your losses, if you expect a tax break of some kind.  If your casino losses do not exceed the standard deduction amount according to the IRS, your losses will come of no use in helping you receive a tax break.

The best way to keep track of your casino winnings is by keeping a very detailed gambling diary.  This is a healthy habit to do anyways, for it serves as a great personal reference in determining for yourself how much money you are winning or losing over the course of a year.  The diary should include the date and time of each gambling session, the casino game(s) played, the name and location of the casino, as well as the names of any witnesses if possible.  Airline tickets to Vegas, as well as hotel and restaurant fees cannot be claimed unless you are claiming your losses as a legitimate business expense.

The way to file your winnings and offsetting losses with the IRS is by first reporting your casino gambling winnings in the "Other Income" box on Form 1040.  If you were given a W-2G or a 1099 MISC by a casino for winning more than $1,200 at any single time, like a slot machine jackpot, or over $600 at a casino tournament, you will be required to provide a copy of these with your return.  You are also required to report any cash transactions over $10,000 in a 24 hour period, whether the money was used to gamble with or not. (This is for money laundering preventions and does not entail taxed income).

After recording all winnings, you can then list all losses on a Schedule A under the category Miscellaneous Deductions.  If your total deductions surpasses the standard deduction, you can expect a break on your taxes.